HPLC Column, Hyper Similars C8 Octyl, 3um, 4.0mm ID x 250mm Length, 150A. Cogent Brand. 1 EA. Special Order Item.
Additional Information:
Hyper Similars C8™ Octyl is a traditional reversed-phase HPLC stationary phase designed for laboratories seeking a reliable alternative to established C8 methods and legacy column platforms. Part of the Cogent™ Similars product line, it is manufactured using high-purity Type-B spherical silica with a bonded octyl (C8) ligand and full endcapping for dependable chromatographic performance. The silica surface characteristics closely resemble those found in Thermo Fisher Hypersil™ and Spherisorb® columns, making this USP L7 stationary phase well suited for method transfer, validation, and replacement of discontinued C8 columns while maintaining familiar retention and selectivity characteristics.
62308-25P-4 is a 250 mm x 4.0 mm ID analytical column packed with 3 µm, 150Å Hyper Similars C8 particles. The combination of a longer column length and smaller particle size provides high efficiency, increased theoretical plate counts, and enhanced resolving power for difficult separations. This configuration is particularly useful for impurity profiling, pharmaceutical assays, and complex sample matrices where maximum resolution is preferred over shorter run times. The 4.0 mm ID format is commonly selected for reproducing legacy methods, while typical operating flow rates are approximately 0.8–1.5 mL/min on conventional HPLC systems. As with most 3 µm columns, higher operating backpressure should be anticipated compared to 5 µm packings.
This column is ideal for hydrophobic and neutral compounds analyzed by reversed-phase HPLC when less retention is desired than a comparable C18 phase. Common uses include pharmaceutical analysis, environmental testing, long-chain fatty acid separations, quality control, and method development. This product is supplied as a Special Order Item manufactured specifically upon receipt of order.
Key Benefits
Type-B spherical silica stationary phase
Suitable alternative for USP L7 methods
Comparable selectivity to Hypersil® and Spherisorb® C8 columns
Increased resolution from 250 mm column length
Higher efficiency with 3 µm particles
Sharper peaks and improved separation performance
Less retention than C18 columns
End-capped octyl (C8) bonded phase
Typical Applications
USP L7 methods
Reversed-phase HPLC
Pharmaceutical analysis
Impurity profiling
Method development
Long-chain fatty acid analysis
Environmental testing
Method transfer and validation
Specifications
Product Type: HPLC Column
Stationary Phase: Hyper Similars C8 Octyl
USP Classification: L7
Particle Size: 3 µm
Particle Type: Type-B Spherical Silica
Bonded Phase: C8 (Octyl)
Endcapped: Yes
Pore Size: 150Å
Column Dimensions: 4.0 mm ID x 250 mm
Length: 250 mm
Recommended Flow Rate: 0.8–1.5 mL/min
Brand: Cogent
Special Order Item Information
This item is a Special Order Item manufactured specifically to customer requirements.
Special Order Items cannot be canceled or returned once an order has been placed.
Manufactured upon receipt of order.
May have extended lead times compared to stocked products.
Important Notes
Designed for reversed-phase chromatography
Longer column length provides increased resolving power
3 µm particles provide higher efficiency and sharper peaks
Higher backpressure than comparable 5 µm columns
Compatible with conventional HPLC systems
Provides less retention than comparable C18 stationary phases
Special Order Item